La Liga have asked the Spanish football federation (RFEF) to play Villarreal's home match against Atletico Madrid on Dec. 6, in Miami.
Last season they tried and failed to move Barcelona’s January clash with Girona to Miami, as the RFEF disagreed.
"We hope that this time we can carry out this positive action for everyone, as other leagues like the NFL or the NBA do when they stage matches overseas," said La Liga president Javier Tebas.
Villarreal season ticket holders will be offered various options to pay them back for not being able to attend the game.
They can choose between travel to Miami to watch the match live, limited to 600 fans, 40 per cent off their next season ticket, or a ticket to watch the game between Atletico and Villarreal at the Wanda Metropolitano (3,000 fans).
Here is what the clubs had to say:
Atletico CEO Miguel Angel Gil: “Atlético de Madrid works every season to expand and improve our brand across all continents and this match in the United States will allow us to keep working on this. Furthermore, we will be able to bring Spanish football closer to fans who live outside of our country. It will be a great occasion that marks the future.”
Villarreal president Fernando Roig: “The United States is a very important country, where Villarreal already has official academies and and carries out different activities for the development of football. For this reason it will be very special for us to be able to play there. We have thought of many different compensation plans for our season ticket holders so that this can be a positive experience for everyone.”